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高剂量与标准剂量的每日两次胸部放疗在局限期小细胞肺癌中的对比研究:最终生存数据、长期毒性及复发模式分析

SCI天天读  · 公众号  ·  · 2025-05-04 20:00
    

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SCI 4 May  2025 High-dose versus standard dose twice-daily thoracic radiotherapy in limited stage small-cell lung cancer: final survival data, long-term toxicity and relapse patterns in a randomised, open-label, phase II trial (Journal of Thoracic Oncology, IF: 21.1) Bjørn Henning Grønberg, Kristin Toftaker Killingberg, Øystein Fløtten, Maria Moksnes Bjaanæs, Odd Terje Brustugun, Tesfaye Madebo, Seppo Wang Langer, Signe Lenora Risumlund, Tine Schytte, Nina Helbekkmo, Kirill Neumann, Øyvind Yksnøy, Jens Engleson, Sverre Fluge, Thor Naustdal, Liv Ellen Giske, Jan Nyman, Georgios Tsakonas, Tarje Onsøien Halvorsen CORRESPONDENCE TO: bjorn.h.gronberg@ntnu.no Introduction  引言 Chemoradiotherapy is standard treatment for limited stage (LS) small cell lung cancer (SCLC). A majority of patients relapse and there is a need for better treatment. We investigated whether twice-daily thoracic radiotherapy (TRT) of 60 Gy/40 fractions improve survival compared with the established schedul ………………………………

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