一周快讯：本周表观文献精选（2019.8.17）

编者按本周我们精选了近一周发表的优秀文献与你共享，如果你对我们选取的文献有自己深入的解读和见解，欢迎投稿【Plus深读】栏目，在23plus上分享你的视角和思维，这是一个展示的舞台，也许也是一段友情，一次合作的起点哦！本期文章：Cell Death & Disease：The POU4F2/Brn-3b transcription factor is required for the hypertrophic response to angiotensin II in the heartNature genetics：Single-cell DNA replication profiling identifies spatiotemporal developmental dynamics of chromosome organizationNature communications：Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesisNature communications：The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in natureMolecular Cell：Dynamic Enhancer DNA Methylati ………………………………