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Phase Ib/II Data of ALK-1 Combo Study Published in BMC Medicine

开拓药业  · 公众号  ·  · 2023-10-28 09:08
Suzhou, October 28, 2023 - Kintor Pharmaceutical Limited (“Kintor Pharma”, HKEX: 9939), a clinical-stage biotechnology company developing innovative small molecule and biological therapeutics, today announced that the results of the Phase Ib/II clinical trial of ALK-1 antibody GT90001 combined with PD-1 antibody nivolumab in the treatment of advanced hepatocellular carcinoma (HCC) were published online by the well-known journal BMC Medicine (Impact factor: 11.806). The results showed that this combination regimen is well-tolerated and has promising anti-tumor activity in patients with recurrent advanced HCC, with a confirmed overall response rate (ORR) of 30% and a remarkable long-tail effect.https://doi.org/10.1186/s12916-023-03098-wHCC is a common pathological type of liver cancer. The early clinical symptoms are not obvious, and 50% of patients are already in the advanced stage when diagnosed. Systemic therapy is recommended for advanced HCC. In recent years, the treatment of ad ………………………………

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